hemangioblast

(noun)

A primitive mesodermal cell that is the precursor of endothelial cells and of blood.

Related Terms

Examples of hemangioblast in the following topics:

  • Development of Blood and Blood Vessels

    • The former requires differentiation of endothelial cells from hemangioblasts and then organization into a primary capillary network.
    • This led to the hypothesis that the two lineages come from the same precursor, termed hemangioblast.
    • Even though there is evidence that corroborates a hemangioblast, the isolation and exact location in the embryo has been difficult to pinpoint.
    • Then in 1932, Murray detected the same event and coined the term hemangioblast.
    • Further evidence to corroborate hemangioblasts comes from the expression of various genes such as CD34 and Tie2 by both lineages.

  • Development of Blood

    • Blood islands form in the yolk sac of an embryo by cellular differentiation of hemangioblasts into endothelial cells.