Section 3
Eukaryotic Gene Regulation
Book
Version 32
By Boundless
By Boundless
Boundless Biology
Biology
by Boundless
6 concepts
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The Promoter and the Transcription Machinery
When transcription factors bind to the promoter region, RNA polymerase is placed in an orientation that allows transcription to begin.
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Transcriptional Enhancers and Repressors
Enhancers increase the rate of transcription of genes, while repressors decrease the rate of transcription.
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Epigenetic Control: Regulating Access to Genes within the Chromosome
Both the packaging of DNA around histone proteins, as well as chemical modifications to the DNA or proteins, can alter gene expression.
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RNA Splicing
RNA splicing allows for the production of multiple protein isoforms from a single gene by removing introns and combining different exons.
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The Initiation Complex and Translation Rate
The first step of translation is ribosome assembly, which requires initiation factors.
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Regulating Protein Activity and Longevity
A cell can rapidly change the levels of proteins in response to the environment by adding specific chemical groups to alter gene regulation.